Preclinical Testing of New Hydrogel Materials for Cartilage Repair: Overcoming Fixation Issues in a Large Animal Model

Figure 5

μCt visualization of bone lysis 4 weeks after implantation of nonreinforced and PCL-reinforced constructs in superficial osteochondral defects. Severe bone lysis was found in all defects regardless of the implanted construct. A reference d0 scan is shown, indicating the original defect depth, as well as a chondral defect showing no bone lysis. Scale bar: 2 mm.