The N-Terminal Domain of Y-Box Binding Protein-1 Induces Cell Cycle Arrest in G2/M Phase by Binding to Cyclin D1
Figure 5
Cells incubated with the three APYBGFP proteins show significant apoptosis. (a) Rat hepatoma cells incubated with each of the fusion proteins were stained with FITC-conjugated annexin V and subjected to FACS analysis. Panel C shows the number of cells (percentage) that have taken up the fusion proteins as quantitated by FACS analysis. (b) Agarose gel electrophoresis of DNA isolated from cells incubated with the fusion. (c) Percentage of cells taken up the fusion protein as quantitated by FACS analysis.
