The Response of Creatine Kinase Specific Activity in Rat Pituitary to Estrogenic Compounds and Vitamin D Less-Calcemic Analogs

Figure 2

Stimulation of creatine kinase (CK) specific activity by different estrogenic compounds with and without raloxifene (Ral; cross-hatches bars) in pituitary from immature (a) and from ovariectomized female rats (Ovx; b). Rats were treated and assayed for CK activity as described in Section 2. Results are means ± SEM for 𝑛=5−15 rats/group. Experimental means compared to control means: ^∗𝑃<.05 and ^∗∗𝑃<.01. Basal activity in Pi from intact rats was 1.22+0.27𝜇mol/min/mg protein and from Ovx was 0.67+0.22𝜇mol/min/mg protein.

(a)

(b)