The Response of Creatine Kinase Specific Activity in Rat Pituitary to Estrogenic Compounds and Vitamin D Less-Calcemic Analogs

Figure 3

Stimulation of creatine kinase (CK) specific activity by different estrogenic compounds with and without E₂ in pituitary from immature (a) and from ovariectomized female rats (Ovx; b). Rats were treated and assayed for CK activity as described in Section 2. Results are means ± SEM for 𝑛=5−15 rats/group. Experimental means compared to control means: ^∗𝑃<.05 and ^∗∗𝑃<.01. Basal activity in organs from immature and OVX rats were 1.02+0.15𝜇mol/min/mg protein and 0.67+0.22𝜇mol/min/mg protein, respectively.

(a)

(b)