The Response of Creatine Kinase Specific Activity in Rat Pituitary to Estrogenic Compounds and Vitamin D Less-Calcemic Analogs

Figure 6

Stimulation of creatine kinase (CK) specific activity by licorice (L), glabridin (Gla) with and without E₂ in pituitary from immature (a) or from Ovx female rats (b). Rats were fed for different time periods as indicated and assayed for CK activity as described in Section 2. Results are means ± SEM for 𝑛=5−10 rats/group. Experimental means compared to control means: ^∗𝑃<.05 and ^∗∗𝑃<.01. Basal activity in Pi from immature rats was 0.97+0.22𝜇mol/min/mg protein and from Ovx rats was 0.67+0.18𝜇mol/min/mg protein.

(a)

(b)