Alteration of Sarcoplasmic Reticulum Ca²⁺ Release in Skeletal Muscle from Calpain 3-Deficient Mice

Figure 2

Effect of caffeine on [Ca²⁺]_i in isolated myoblasts and myotubes. Representative traces show the typical time course of the response to 20 mM caffeine observed in (a) wild type (+/+) myoblast; (b) wild type (+/+) myotube; (c) capn3-deficient (−/−) myoblast; (d) capn3-deficient (−/−) myotube. The duration of drug exposure is represented (open bars).

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(b)

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