International Journal of Cell Biology / 2009 / Article / Fig 4

Research Article

Alteration of Sarcoplasmic Reticulum Release in Skeletal Muscle from Calpain 3-Deficient Mice

Figure 4

Effect of caffeine and CPA on [Ca2+]i in isolated myoblasts and myotubes. Representative traces show the typical time course of the response to 20 mM caffeine and 10  πœ‡ M CPA observed in (a) wild type (+/+) myoblast; (b) wild type (+/+) myotube; (c) calpain 3-deficient (βˆ’/βˆ’) myoblast; (d) calpain 3-deficient (βˆ’/βˆ’) myotube. The duration of exposure to caffeine (open bars) and CPA (gray-dashed bars) is represented.
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340346.fig.004b
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