Alteration of Sarcoplasmic Reticulum Release in Skeletal Muscle from Calpain 3-Deficient Mice
Figure 4
Effect of caffeine and CPA on [Ca2+]i in isolated myoblasts and myotubes. Representative traces show the typical time course of the response to 20 mM caffeine and 10 M CPA observed in (a) wild type (+/+) myoblast; (b) wild type (+/+) myotube; (c) calpain 3-deficient (−/−) myoblast; (d) calpain 3-deficient (−/−) myotube. The duration of exposure to caffeine (open bars) and CPA (gray-dashed bars) is represented.
