Role of BMP-4 and Its Signaling Pathways in Cultured Human Melanocytes

Figure 5

BMP-4 decreases the intracellular level of cAMP. Paired cultures of melanocytes were treated with BMP-4 for 0, 1, 18, 24, and 48 hours. At each time point, cells were harvested and the level of intracullelar cAMP level was determined. One representative result from three separate experiments is shown.