Review Article
Molecular Mechanisms Involved in Mesenchymal Stem Cell Migration to the Site of Acute Myocardial Infarction
Table 2
Expression of chemokine receptor mRNA by human and murine bone marrow derived MSC as determined by microarray or qRT-PCR and flow cytometry.
| | Chemokine receptor | mRNA | Cell surface protein | Intracellular protein |
| | Human | Mouse | Human | Mouse | Human | Mouse | | CCR1 | − | + | +/− | ND | + | ND | | CCR2 | − | − | | − | | − | | CCR3 | − | − | − | − | + | − | | CCR4 | − | − | ND | ND | ND | ND | | CCR5 | + | + | − | − | − | + | | CCR6 | − | − | ND | ND | ND | ND | | CCR7 | − | + | ND | − | ND | + | | CCR8 | + | + | +/− | − | − | ND | | CCR9 | − | + | ND | − | ND | ND | | CCR10 | + | + | − | − | +/− | ND | | CCR11 | + | + | +/− | ND | − | ND | | CXCR1 | − | − | ND | ND | ND | ND | | CXCR2 | − | − | ND | ND | ND | ND | | CXCR3 | − | − | − | ND | + | ND | | CXCR4 | − | + | − | − | + | + | | CXCR5 | − | − | | + | ND | ND | | CXCR6 | − | + | + | + | + | ND | | CXCR7 | ND | − | ND | ND | ND | ND | | CX3CR1 | − | − | ND | ND | ND | ND |
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−, not detected; +/−, weak expression, +, strong expression; ND, no data
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