Contribution of Filopodia to Cell Migration: A Mechanical Link between Protrusion and Contraction

Figure 9

Lateral filopodia and adhesion proteins. Live cell time-lapse of a cell co-transfected with mCherry-actin and zyxin-GFP. Turquoise arrowheads indicate the localization of zyxin to the proximal end of stationary filopodia. Pink arrowheads indicate a lateral filopodium which is associated with zyxin along its entire length. White boxes indicate the areas that are enlarged in order to show the details of stationary and lateral filopodia. The entire movie can be found in Supplementary Data, Movie 11. Scale Bar 10 𝜇m.