Interferonβ-1b Induces the Expression of RGS1 a Negative Regulator of G-Protein Signaling
Figure 2
Induction of RGS1 by IFN-β, IFN-γ, and PMA. PBMCs obtained from healthy individuals were stimulated and RGS1 expression determined as described in Section 2. PBMCs were stimulated with IFN-β (1000 IU/mL), IFN-γ (1000 IU/mL), and PMA (2 ng/mL) for the times indicated (white column = 4 hours; gray column = 18 hours post-IFN-β stimulation). All results were normalized to GAPDH and expressed as the mean ± SD, . *.
