Acute Immobilization Stress Modulate GABA Release from Rat Olfactory Bulb: Involvement of Endocannabinoids—Cannabinoids and Acute Stress Modulate GABA Release

<table>Glutamate stimulated 3H-GABA release from olfactory bulb: effect of cannabinoids. Micro dissected EPL was incubated with 0.1 <i>μ</i>M 3H-GABA and superfused with Krebs bicarbonate; after a wash of 35 min and 14 min of basal release, 100 <i>μ</i>M of Glu was added for 4 min followed after 22 min by 30 mM KCl stimulation (-▲-). The cannabinoid agonist methanandamide (AEA)(10 <i>μ</i>M) was added 14 min before, during, and 12 min after Glu stimulation (-□-). The CB1 antagonist AM281 (10 <i>μ</i>M) was added together with AEA in another set of experiments (-■-). Results are expressed as % of the total 3H-GABA remaining in the tissue at the time of collection, released per minute of one representative experiment.</table>

International Journal of Cell Biology

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Figure 2: Acute Immobilization Stress Modulate GABA Release from Rat Olfactory Bulb: Involvement of Endocannabinoids—Cannabinoids and Acute Stress Modulate GABA Release 

Figure 2 | Acute Immobilization Stress Modulate GABA Release from Rat Olfactory Bulb: Involvement of Endocannabinoids—Cannabinoids and Acute Stress Modulate GABA Release 