Research Article

PAI-1 Expression Is Required for HDACi-Induced Proliferative Arrest in ras-Transformed Renal Epithelial Cells

Figure 3

NaB suppressed cell growth in serum-free or supplemented culture conditions. Proliferative restriction was maximal at 10 mM resulting in final population densities of just 47% (a) and 52% (b) compared to respective controls. Data plotted is the mean ± standard deviation for triplicate assessments of final cell densities (i.e., % confluency) for each NaB concentration under the two growth conditions.
710974.fig.003a
(a)
710974.fig.003b
(b)