International Journal of Cell Biology / 2011 / Article / Fig 1

Research Article

ATP-Sensitive Potassium Channel Currents in Eccentrically Hypertrophied Cardiac Myocytes of Volume-Overloaded Rats

Figure 1

Voltage-Current Relationships in Sham-Operated Control Rats. Sarcolemmal outward potassium current (I), expressed as current density (pA/pF), in patches of ventricular myocytes from adult control rats subjected to a sham surgical operation, treatment with the ATP-sensitive potassium channel (KATP) agonist cromakalim (100 μM), and post-treatment with the KATP antagonist glibenclamide (5 μM). The membrane voltage was clamped at steps of 10 mV from −80 mV to +40 mV. Differences in pA/pF in the presence and absence of treatment with cromakalim, and post-treatment with glibenclamide were significant only at the voltages from −20 mV to +40 mV ( ).
838951.fig.001

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19.