Treatment with Y-27632, a ROCK Inhibitor, Increases the Proinvasive Nature of SW620 Cells on 3D Collagen Type 1 Matrix
Figure 1
SW620 cells were seeded at different densities: 50 × 103 (a), and 250 × 103 cells/cm2 (b). The lower seeding density (a) shows rounder cells with few cell-cell contacts. The greater seeding density allows for more cell-cell contact, creating a more epithelial state. Scale Bar = 10 μm.