Treatment with Y-27632, a ROCK Inhibitor, Increases the Proinvasive Nature of SW620 Cells on 3D Collagen Type 1 Matrix
Figure 2
ROCK activities of SW620 cells seeded at 50 × 103 and 250 × 103 cells/cm2 and allowed to invade into 1.5 mg/mL collagen scaffolds. Cells seeded at the higher density had over double the ROCK activity compared to those seeded at the lower density. The number of cells was kept constant between the two conditions while the seeding area was altered.
