Review Article

Transmission Electron Microscopy Studies of Cellular Responses to Entry of Virions: One Kind of Natural Nanobiomaterial

Figure 1

Electron micrographs of Bombyx mori midgut cells perorally inoculated with BmCPV-1. (a) Cross-section of microvilli (Mv) showing different stages of virus entry into midgut columnar cells. Intact virions were seen to adhere to (open arrow), penetrate (filled arrows), and be inside (arrowhead) the microvilli. Insert: higher magnification of a virion penetrating the membrane. (b) Virions (arrows) were detected in the goblet chamber (GCh) and in the cytoplasmic projections (CP) and the cytoplasm of the goblet cell (GC). (c) Virions (arrows) were distributed among myofibrils in the cytoplasm of midgut muscle cell (MC). Several virions (arrowheads) occurred in the haemocoel (H). Bars = 100 nm [11].
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