Modulation of Tumor Cell Survival, Proliferation, and Differentiation by the Peptide Derived from Tenascin-C: Implication of β1-Integrin Activation

Figure 3

Apoptosis was induced on Ramos cells with TNIIIA2 administration. (a) Hoechst staining of Ramos cells treated with TNIIIA2. (b) Effect of caspase inhibitors on Ramos cell survival, treated with TNIIIA2. (c) Cell surface exposure of phosphatidylserine on Ramos cell treated with TNIIIA2 (figures were modified from Figure 2 of [19]). *𝑃<0.05 versus TNIIIA2 single treated sample, **𝑃<0.05 versus untreated control.

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