Modulation of Tumor Cell Survival, Proliferation, and Differentiation by the Peptide Derived from Tenascin-C: Implication of β1-Integrin Activation
Figure 5
Adhesion dependent acceleration of hemin-induced erythroid differentiation of K562 cells. (a, b) Effect of TNIIIA2 on erythroid differentiation of K562 cells, induced by hemin. Typical image of erythroid differentiation was shown in (a). (c) Effects of antagonist for VLA5 (RGD) and VLA4 (CS-1) on TNIIIA2-induced acceleration of erythroid differentiation (figures were modified from Figures 2(a), 3(a), and 3(c) of [45]). * versus Hemin single treated sample, ** versus Hemin and TNIIIA2 treated sample.
