Modulation of Tumor Cell Survival, Proliferation, and Differentiation by the Peptide Derived from Tenascin-C: Implication of <i>β</i>1-Integrin Activation

<table>TNIIIA2 protects cells from anoikis by activating the <i>β</i>1-integrin. (a) Time-course study of the effect of cell-detachment in survival/proliferation of NIH3T3 cells. (b) Effect of inhibition of apoptosis (Z-VAD) or <i>α</i>5<i>β</i>1 integrin signal (anti-<i>α</i>5 Ab and RGD peptide) in detachment-induced cell death (our unpublished observation).</table>

International Journal of Cell Biology

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Figure 6

Figure 6: Modulation of Tumor Cell Survival, Proliferation, and Differentiation by the Peptide Derived from Tenascin-C: Implication of <i>β</i>1-Integrin Activation 

Figure 6 | Modulation of Tumor Cell Survival, Proliferation, and Differentiation by the Peptide Derived from Tenascin-C: Implication of β1-Integrin Activation 