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International Journal of Cell Biology
Volume 2012, Article ID 672462, 9 pages
Research Article

Distinct MicroRNA Subcellular Size and Expression Patterns in Human Cancer Cells

1Laboratory of Bioinformation and Noncoding RNA and Center for Systems Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
2Graduate University of Chinese Academy of Sciences, Beijing 100080, China

Received 27 July 2011; Accepted 9 November 2011

Academic Editor: Ivana De La Serna

Copyright © 2012 Beibei Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Figure S1. Length distribution of small RNAs in MDA-MB-231.

Figure S2. The small RNA genome location distribution near or within the coding genes.

Figure S3. Western bolt. Analysis of expression of Lamin A/C, GAPDH and beta-action in the extracts of nucleus, cytoplasma and whole cell.

Table S1. Total sequencing small RNAs genome mapping.

Table S2. Small RNA sequences annotation.

Table S3. The relationship between small RNAs loci and coding genes loci.

Table S4. The nuclear small RNAs annotated as known piRNAs.

Table S5. Predicted new microRNAs.

Table S6. Isoforms of microRNAs.

Table S7. MicroRNAs NCR values varied significantly between different cell lines.

  1. Supplementary Material 1
  2. Supplementary Material 2
  3. Supplementary Material 3