Distinct MicroRNA Subcellular Size and Expression Patterns in Human Cancer Cells

Table 1

Expression level and sub-cellular distributions of miRNA in two breast cancer cell lines.

miRNA	MDA-MB231				MCF-7
	Total Reads*	NCR (log2)	𝑁 reads**	𝐶 reads**	Total Reads*	NCR (log2)	𝑁 reads**	𝐶 reads**
Hsa-miR-27b	56565	1.73	43463	13102	24084	−1.09	7700	16384
Hsa-miR-29a	5811	3.05	5185	626	1976	−1.93	410	1565
Hsa-miR-29c	172226	~0	86113	86113	23259	−1.93	4835	18424

The sequencing data for MDA-MB231 and MCF-7 in GSE16579 were downloaded from the Gene Expression Omnibus (GEO). Adapter sequences were removed from reads. Filtered reads with lengths from 18 nt to 25 nt were annotated using MirBase, v.16.0 by BLAST with at 100% identify (0 mismatch).
*Total Reads obtained from GSE16579.
** 𝑁- and 𝐶-reads are reads number in nucleus and cytoplasm, respectively. These were calculated from Total Reads and the NCR.