Formulation Changes Affect Material Properties and Cell Behavior in HA-Based Hydrogels
Figure 2
Time required to fully degrade hydrogels using 5, 10, or 50 U/mL hyaluronidase (HAse) in PBS; 0.2, 0.5, or 2.0 mg/mL collagenase (Case) in PBS; or a combination of 5 U/mL HAse and 0.2 mg/mL Case in PBS. Hydrogels in PBS without enzyme did not degrade. The dashed line indicates the point at which the experiment was terminated (814 hrs). for each formulation in each enzyme solution; values are mean ± SD.
