Review Article
The Actin-Bundling Protein L-Plastin: A Critical Regulator of Immune Cell Function
Table 1
The kinases that regulate phosphorylation of LPL in response to various cell stimuli are listed, along with the inhibitor used to test the participation of each kinase. The kinases that phosphorylate LPL in other cell types, such as T cells and macrophages, have not yet been defined. References are numbered according to appearance in the text.
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Abbreviations: FcγR: receptor for the Fc portion of immunoglobulin; IC: immune complexes; fMLP: N-formyl-L-methionyl-L-leucyl-L-phenylalanine; PKA: protein kinase A; PI3K: phosphatidylinositol 3-kinase; PKC: protein kinase C; FPR: formyl peptide receptor; FPR-L1: formyl peptide receptor-like 1; PLD: phospholipase D; GM-CSF: granulocyte macrophage colony stimulating factor; GMR: GM-CSF receptor. |