Trimeric Tau Is Toxic to Human Neuronal Cells at Low Nanomolar Concentrations

Figure 1

Tau protein structural features in linear diagram. A full-length tau protein with 441 amino acids (tau441 or tau 2N4R) is shown. Alternative splicing showed in yellow rectangles results in a total of six isoforms, denoted by either their total number of amino acids or the number of N′-terminal exons (Ns) and microtubule-associated repeats (Rs).