Identification of Misfolded Proteins in Body Fluids for the Diagnosis of Prion Diseases

Figure 1

RT-QuIC reactions seeded with 15 µL of human CSF samples from one Italian sporadic CJD patient (12076) and one non-CJD control (13004). 100 fg of 263K prion-infected hamster brain homogenate were used to seed positive control reactions. Each sample was processed in duplicate.