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International Journal of Cell Biology
Volume 2013, Article ID 843781, 9 pages
http://dx.doi.org/10.1155/2013/843781
Review Article

Expression of Tra2β in Cancer Cells as a Potential Contributory Factor to Neoplasia and Metastasis

1Institute of Genetic Medicine, Newcastle University, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK
2Institute of Cellular Medicine, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK

Received 2 May 2013; Accepted 9 June 2013

Academic Editor: Claudia Ghigna

Copyright © 2013 Andrew Best et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [18 citations]

The following is the list of published articles that have cited the current article.

  • Andrew Best, Katherine James, Caroline Dalgliesh, Elaine Hong, Mahsa Kheirolahi-Kouhestani, Tomaz Curk, Yaobo Xu, Marina Danilenko, Rafiq Hussain, Bernard Keavney, Anil Wipat, Roscoe Klinck, Ian G. Cowell, Ka Cheong Lee, Caroline A. Austin, Julian P. Venables, Benoit Chabot, Mauro Santibanez Koref, Alison Tyson-Capper, and David J. Elliott, “Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons,” Nature Communications, vol. 5, pp. 4760, 2014. View at Publisher · View at Google Scholar
  • Andrew Best, Caroline Dalgliesh, Mahsa Kheirollahi‑Kouhestani, Marina Danilenko, Ingrid Ehrmann, Alison Tyson‑Capper, and David J. Elliott, “Tra2 protein biology and mechanisms of splicing control,” Biochemical Society Transactions, vol. 42, no. 4, pp. 1152–1158, 2014. View at Publisher · View at Google Scholar
  • Erin M. Siegel, Steven Eschrich, Kathryn Winter, Bridget Riggs, Anders Berglund, Abidemi Ajidahun, Jeff Simko, Jennifer Moughan, Jaffer Ajani, Anthony Magliocco, Abul Elahi, Sarah Hoffe, and David Shibata, “Epigenomic Characterization of Locally Advanced Anal Cancer,” Diseases of the Colon & Rectum, vol. 57, no. 8, pp. 941–957, 2014. View at Publisher · View at Google Scholar
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  • Markus Storbeck, Kristina Hupperich, John Antonydas Gaspar, Kesavan Meganathan, Lilian Martinez Carrera, Radu Wirth, Agapios Sachinidis, and Brunhilde Wirth, “Neuronal-Specific Deficiency of the Splicing Factor Tra2b Causes Apoptosis in Neurogenic Areas of the Developing Mouse Brain,” Plos One, vol. 9, no. 2, 2014. View at Publisher · View at Google Scholar
  • Sarika Jalan, Krishna Kanhaiya, Aparna Rai, Obul Reddy Bandapalli, and Alok Yadav, “Network Topologies Decoding Cervical Cancer,” Plos One, vol. 10, no. 8, 2015. View at Publisher · View at Google Scholar
  • Vui King Vincent-Chong, Iman Salahshourifar, Rozaimi Razali, Arif Anwar, and Rosnah Binti Zain, “Immortalization of epithelial cells in oral carcinogenesis as revealed by genome-wide array comparative genomic hybridization: A meta-analysis,” Head & Neck, 2015. View at Publisher · View at Google Scholar
  • Lixiang Yang, Tao Tao, Yunfeng Wang, Zhen Bao, Xiaojuan He, and Gang Cui, “Knocking down the expression of TRA2β inhibits the proliferation and migration of human glioma cells,” Pathology - Research and Practice, 2015. View at Publisher · View at Google Scholar
  • Weijin Xu, Huixing Huang, Long Yu, and Lihuan Cao, “Meta-analysis of gene expression profiles indicates genes in spliceosome pathway are up-regulated in hepatocellular carcinoma (HCC),” Medical Oncology, vol. 32, no. 4, 2015. View at Publisher · View at Google Scholar
  • Andrew Best, Katherine James, Gerald Hysenaj, Alison Tyson-Capper, and David J. Elliott, “Transformer2 proteins protect breast cancer cells from accumulating replication stress by ensuring productive splicing of checkpoint kinase 1,” Frontiers of Chemical Science and Engineering, 2015. View at Publisher · View at Google Scholar
  • Ander Aramburu, Isabel Zudaire, María J. Pajares, Jackeline Agorreta, Alberto Orta, María D. Lozano, Alfonso Gúrpide, Javier Gómez-Román, Jose A. Martinez-Climent, Jacek Jassem, Marcin Skrzypski, Milind Suraokar, Carmen Behrens, Ignacio I. Wistuba, Ruben Pio, Angel Rubio, and Luis M. Montuenga, “Combined clinical and genomic signatures for the prognosis of early stage non-small cell lung cancer based on gene copy number alterations,” BMC Genomics, vol. 16, no. 1, 2015. View at Publisher · View at Google Scholar
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  • Guo Zhaozhong, Jia Jun, Jia Rong, Liu Peiqi, Yin Yaotian, and Guo Jihua, “Expression of SRSF3 is correlated with carcinogenesis and progression of oral squamous cell carcinoma,” International Journal of Medical Sciences, vol. 13, no. 7, pp. 533–539, 2016. View at Publisher · View at Google Scholar
  • Yuki Kuwano, Kiyoshi Masuda, Kazuhito Rokutan, Saki Saijo, Tatsuya Nishikawa, and Kensei Nishida, “Serine/arginine-rich splicing factor 7 regulates p21-dependent growth arrest in colon cancer cells,” Journal of Medical Investigation, vol. 63, no. 3-4, pp. 219–226, 2016. View at Publisher · View at Google Scholar
  • Tieju Liu, Yi Wang, Huizhi Sun, Xueyi Dong, Fang Liu, Xiaohui Liang, Baocun Sun, Dongwang Zhu, Chen Chen, Bing Shao, and Meili Wang, “TRA2A promoted paclitaxel resistance and tumor progression in triple-negative breast cancers via regulating alternative splicing,” Molecular Cancer Therapeutics, vol. 16, no. 7, pp. 1377–1388, 2017. View at Publisher · View at Google Scholar
  • Rebekah Eleazer, Matthew Rea, Yvonne Fondufe-Mittendorf, and Meredith Eckstein, “Epigenomic reprogramming in inorganic arsenic-mediated gene expression patterns during carcinogenesis,” Reviews on Environmental Health, vol. 32, no. 1-2, pp. 93–103, 2017. View at Publisher · View at Google Scholar
  • Jian Liu, Tingting Bian, Jia Feng, Li Qian, Jianguo Zhang, Daishan Jiang, Qing Zhang, Xiaoli Li, Yifei Liu, and Jiahai Shi, “miR-335 inhibited cell proliferation of lung cancer cells by target Tra2β,” Cancer Science, 2017. View at Publisher · View at Google Scholar
  • Liang Zeng, Zhihong Liu, Xiyun Deng, Jingmin Zhong, Guangchun He, Fangjun Li, Jing Li, Wen Zhou, Wenbin Liu, Yun Zhang, and Sanqian Huang, “Identification of Nucleobindin-2 as a Potential Biomarker for Breast Cancer Metastasis Using iTRAQ-based Quantitative Proteomic Analysis.,” Journal of Cancer, vol. 8, no. 15, pp. 3062–3069, 2017. View at Publisher · View at Google Scholar