Necrostatin-1 Reduces Neurovascular Injury after Intracerebral Hemorrhage

Figure 3

Nec-1 reduces cell death after ICH. Nec-1 administration at the time of ICH reduced perihematomal cell death, as assessed by PI staining. Top panels are representative images from placebo- or Nec-1-treated mice following ICH. Bottom panel depicts the quantification of PI staining following treatment with Nec-1 or Nec-1_inactive. Cell counts were normalized to placebo-treated ICH mice. Data are expressed as mean ± SEM (^∗∗𝑃<0.01 versus placebo; 𝑛=5 per group).