Necrostatin-1 Reduces Neurovascular Injury after Intracerebral Hemorrhage
Figure 6
Nec-1 reduced edema development after ICH. Mice were administered Nec-1 or Nec- at the time of collagenase-induced ICH. Brain water content, a measure of cerebral edema, was assessed in the ipsilateral hemisphere at (a) 24 h or (b) 72 h following ICH. Comparisons within each hemisphere between different treatment groups were done using a one-way ANOVA followed by Student-Newman-Keuls post hoc test (, ). Data are expressed as mean ± SEM from 10 mice per group.
