Effect of Serum and Oxygen Concentration on Gene Expression and Secretion of Paracrine Factors by Mesenchymal Stem Cells

Table 2

Paracrine factors in media.

	Normoxia		Hypoxia
	5%	20%	5%	20%
VEGF ()	1447.7 ± 93.5^a	2102.37 ± 138.7	1601.17 ± 66.3^a	2247.37 ± 83.6
MCP-1 ()	3964.4 ± 244.9^a	4985.1 ± 160.1	1880.0 ± 141.3^ab	2705.7 ± 143.8^b
MIP-1α ()	5.8 ± 0.4	6.2 ± 0.2	5.3 ± 0.5	6.0 ± 0.4
MIP-1β ()	5.1 ± 0.6	4.1 ± 0.1	4.0 ± 0.1^ab	3.5 ± 0.2^b
MMP-2 ()	37.3 ± 1.0^a	26.8 ± 2.2	28.6 ± 1.3^ab	19.7 ± 0.2^b

Data reported as mean ± SE in pg/mL except for MMP-2 (ng/mL). 5% and 20% refer to the amount of serum supplement present in the media. versus 20%; versus normoxia.