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International Journal of Cell Biology
Volume 2015 (2015), Article ID 369874, 9 pages
http://dx.doi.org/10.1155/2015/369874
Research Article

Intermittent Compressive Stress Enhanced Insulin-Like Growth Factor-1 Expression in Human Periodontal Ligament Cells

1Research Unit of Mineralized Tissue, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand
2Graduate Program in Oral Biology, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand
3Department of Anatomy, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand
4Department of Oral Medicine, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand

Received 27 February 2015; Revised 19 May 2015; Accepted 20 May 2015

Academic Editor: Rony Seger

Copyright © 2015 Jittima Pumklin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. Kitaura, K. Kimura, M. Ishida et al., “Effect of cytokines on osteoclast formation and bone resorption during mechanical force loading of the periodontal membrane,” The Scientific World Journal, vol. 2014, Article ID 617032, 7 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  2. A. D. Berendsen, T. H. Smit, X. F. Walboomers, V. Everts, J. A. Jansen, and A. L. J. J. Bronckers, “Three-dimensional loading model for periodontal ligament regeneration in vitro,” Tissue Engineering Part C: Methods, vol. 15, no. 4, pp. 561–570, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. N. Hacopian, T. H. Nik, M. H. Ghahremani, H. R. Rahimi, and S. N. Ostad, “Effects of continuous and interrupted forces on gene transcription in periodontal ligament cells in vitro,” Acta Medica Iranica, vol. 49, no. 10, pp. 643–649, 2011. View at Google Scholar · View at Scopus
  4. C. A. G. McCulloch, P. Lekic, and M. D. McKee, “Role of physical forces in regulating the form and function of the periodontal ligament,” Periodontology 2000, vol. 24, no. 1, pp. 56–72, 2000. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Kaku, K. Uoshima, Y. Yamashita, and H. Miura, “Investigation of periodontal ligament reaction upon excessive occlusal load—osteopontin induction among periodontal ligament cells,” Journal of Periodontal Research, vol. 40, no. 1, pp. 59–66, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. K. Nozaki, M. Kaku, Y. Yamashita, M. Yamauchi, and H. Miura, “Effect of cyclic mechanical loading on osteoclast recruitment in periodontal tissue,” Journal of Periodontal Research, vol. 45, no. 1, pp. 8–15, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. D. Pavlin and J. Gluhak-Heinrich, “Effect of mechanical loading on periodontal cells,” Critical Reviews in Oral Biology and Medicine, vol. 12, no. 5, pp. 414–424, 2001. View at Publisher · View at Google Scholar · View at Scopus
  8. M. S. Lee, M.-T. Sun, S.-T. Pang et al., “Evaluation of differentially expressed genes by shear stress in human osteoarthritic chondrocytes in vitro,” Chang Gung Medical Journal, vol. 32, no. 1, pp. 42–50, 2009. View at Google Scholar · View at Scopus
  9. L. Li, M.-X. Han, S. Li, Y. Xu, and L. Wang, “Hypoxia regulates the proliferation and osteogenic differentiation of human periodontal ligament cells under cyclic tensile stress via mitogen-activated protein kinase pathways,” Journal of Periodontology, vol. 85, no. 3, pp. 498–508, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. B.-W. Wang, G.-J. Wu, W.-P. Cheng, and K.-G. Shyu, “Mechanical stretch via transforming growth factor-β1 activates microRNA-208a to regulate hypertrophy in cultured rat cardiac myocytes,” Journal of the Formosan Medical Association, vol. 112, no. 10, pp. 635–643, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. K. Kanjanamekanant, P. Luckprom, and P. Pavasant, “Mechanical stress-induced interleukin-1beta expression through adenosine triphosphate/P2X7 receptor activation in human periodontal ligament cells,” Journal of Periodontal Research, vol. 48, no. 2, pp. 169–176, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. P. Luckprom, S. Wongkhantee, T. Yongchaitrakul, and P. Pavasant, “Adenosine triphosphate stimulates RANKL expression through P2Y1 receptor-cyclo-oxygenase-dependent pathway in human periodontal ligament cells,” Journal of Periodontal Research, vol. 45, no. 3, pp. 404–411, 2010. View at Publisher · View at Google Scholar · View at Scopus
  13. S. Wongkhantee, T. Yongchaitrakul, and P. Pavasant, “Mechanical stress induces osteopontin via ATP/P2Y1 in periodontal cells,” Journal of Dental Research, vol. 87, no. 6, pp. 564–568, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. R. M. S. De Araujo, Y. Oba, and K. Moriyama, “Identification of genes related to mechanical stress in human periodontal ligament cells using microarray analysis,” Journal of Periodontal Research, vol. 42, no. 1, pp. 15–22, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. R. M. S. de Araujo, Y. Oba, S. Kuroda, E. Tanaka, and K. Moriyama, “RhoE regulates actin cytoskeleton organization in human periodontal ligament cells under mechanical stress,” Archives of Oral Biology, vol. 59, no. 2, pp. 187–192, 2014. View at Publisher · View at Google Scholar · View at Scopus
  16. Y. Kheralla, W. Götz, A. Kawarizadeh, B. Rath-Deschner, and A. Jäger, “IGF-I, IGF-IR and IRS1 expression as an early reaction of PDL cells to experimental tooth movement in the rat,” Archives of Oral Biology, vol. 55, no. 3, pp. 215–222, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. B. Rath-Deschner, J. Deschner, S. Reimann, A. Jager, and W. Gotz, “Regulatory effects of biomechanical strain on the insulin-like growth factor system in human periodontal cells,” Journal of Biomechanics, vol. 42, no. 15, pp. 2584–2589, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. S. Termsuknirandorn, J. Hosomichi, and K. Soma, “Occlusal stimuli influence on the expression of IGF-1 and the IGF-1 receptor in the rat periodontal ligament,” Angle Orthodontist, vol. 78, no. 4, pp. 610–616, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Raja, G. Byakod, and P. Pudakalkatti, “Growth factors in periodontal regeneration,” International Journal of Dental Hygiene, vol. 7, no. 2, pp. 82–89, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. F. A. M. de Abreu, C. L. Ferreira, G. A. B. Silva et al., “Effect of PDGF-BB, IGF-I growth factors and their combination carried by liposomes in tooth socket healing,” Brazilian Dental Journal, vol. 24, no. 4, pp. 299–307, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. W. Götz, D. Kunert, D. Zhang, A. Kawarizadeh, S. Lossdörfer, and A. Jäger, “Insulin-like growth factor system components in the periodontium during tooth root resorption and early repair processes in the rat,” European Journal of Oral Sciences, vol. 114, no. 4, pp. 318–327, 2006. View at Publisher · View at Google Scholar · View at Scopus
  22. X. Han and S. Amar, “IGF-1 signaling enhances cell survival in periodontal ligament fibroblasts vs. gingival fibroblasts,” Journal of Dental Research, vol. 82, no. 6, pp. 454–459, 2003. View at Publisher · View at Google Scholar · View at Scopus
  23. A. C. P. Sant'Ana, M. M. Marques, E. C. Barroso, E. Passanezi, and M. L. R. de Rezende, “Effects of TGF-beta1, PDGF-BB, and IGF-1 on the rate of proliferation and adhesion of a periodontal ligament cell lineage in vitro,” Journal of Periodontology, vol. 78, no. 10, pp. 2007–2017, 2007. View at Publisher · View at Google Scholar · View at Scopus
  24. Y. Yu, J. Mu, Z. Fan et al., “Insulin-like growth factor 1 enhances the proliferation and osteogenic differentiation of human periodontal ligament stem cells via ERK and JNK MAPK pathways,” Histochemistry and Cell Biology, vol. 137, no. 4, pp. 513–525, 2012. View at Publisher · View at Google Scholar · View at Scopus
  25. J. Li, Z. Yang, Z. Li, L. Gu, Y. Wang, and C. Sung, “Exogenous IGF-1 promotes hair growth by stimulating cell proliferation and down regulating TGF-beta1 in C57BL/6 mice in vivo,” Growth Hormone and IGF Research, vol. 24, no. 2-3, pp. 89–94, 2014. View at Publisher · View at Google Scholar · View at Scopus
  26. R. S. Pais, N. Moreno-Barriuso, I. Hernández-Porras, I. P. López, J. De Las Rivas, and J. G. Pichel, “Transcriptome analysis in prenatal IGF1-deficient mice identifies molecular pathways and target genes involved in distal lung differentiation,” PLoS ONE, vol. 8, no. 12, Article ID e83028, 2013. View at Publisher · View at Google Scholar · View at Scopus
  27. W. Götz, M. Heinen, S. Lossdörfer, and A. Jäger, “Immunohistochemical localization of components of the insulin-like growth factor system in human permanent teeth,” Archives of Oral Biology, vol. 51, no. 5, pp. 387–395, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. P. Proff, C. Reicheneder, A. Faltermeier, D. Kubein-Meesenburg, and P. Römer, “Effects of mechanical and bacterial stressors on cytokine and growth-factor expression in periodontal ligament cells,” Journal of Orofacial Orthopedics, vol. 75, no. 3, pp. 191–202, 2014. View at Publisher · View at Google Scholar
  29. J. Manokawinchoke, N. Limjeerajarus, C. Limjeerajarus, P. Sastravaha, V. Everts, and P. Pavasant, “Mechanical force-induced TGFB1 increases expression of SOST/POSTN by hPDL cells,” Journal of Dental Research, 2015. View at Publisher · View at Google Scholar
  30. J.-Y. Joo, E.-Y. Kwon, and J.-Y. Lee, “Intentional passive eruption combined with scaling and root planing of teeth with moderate chronic periodontitis and traumatic occlusion,” Journal of Periodontal and Implant Science, vol. 44, no. 1, pp. 20–24, 2014. View at Publisher · View at Google Scholar · View at Scopus
  31. S. Nakatsu, Y. Yoshinaga, A. Kuramoto et al., “Occlusal trauma accelerates attachment loss at the onset of experimental periodontitis in rats,” Journal of Periodontal Research, vol. 49, no. 3, pp. 314–322, 2014. View at Publisher · View at Google Scholar · View at Scopus
  32. V. Locatelli and V. E. Bianchi, “Effect of GH/IGF-1 on Bone Metabolism and Osteoporsosis,” International Journal of Endocrinology, vol. 2014, Article ID 235060, 25 pages, 2014. View at Publisher · View at Google Scholar
  33. K.-H. Lau, D. J. Baylink, X.-D. Zhou et al., “Osteocyte-derived insulin-like growth factor I is essential for determining bone mechanosensitivity,” The American Journal of Physiology—Endocrinology and Metabolism, vol. 305, no. 2, pp. E271–E281, 2013. View at Publisher · View at Google Scholar · View at Scopus
  34. M. Kveiborg, A. Flyvbjerg, E. F. Eriksen, and M. Kassem, “Transforming growth factor-β1 stimulates the production of insulin-like growth factor-I and insulin-like growth factor-binding protein-3 in human bone marrow stromal osteoblast progenitors,” Journal of Endocrinology, vol. 169, no. 3, pp. 549–561, 2001. View at Publisher · View at Google Scholar · View at Scopus
  35. H. Ochiai, S. Okada, A. Saito et al., “Inhibition of insulin-like growth factor-1 (IGF-1) expression by prolonged transforming growth factor-β1 (TGF-β1) administration suppresses osteoblast differentiation,” Journal of Biological Chemistry, vol. 287, no. 27, pp. 22654–22661, 2012. View at Publisher · View at Google Scholar · View at Scopus
  36. E. J. Schabort, M. van der Merwe, and C. U. Niesler, “TGF-β isoforms inhibit IGF-1-induced migration and regulate terminal differentiation in a cell-specific manner,” Journal of Muscle Research and Cell Motility, vol. 31, no. 5-6, pp. 359–367, 2011. View at Publisher · View at Google Scholar · View at Scopus
  37. J. Karhausen, V. H. Haase, and S. P. Colgan, “Inflammatory hypoxia: role of hypoxia-inducible factor,” Cell Cycle, vol. 4, no. 2, pp. 256–258, 2005. View at Google Scholar · View at Scopus
  38. H. K. Eltzschig and P. Carmeliet, “Hypoxia and inflammation,” The New England Journal of Medicine, vol. 364, no. 7, pp. 656–665, 2011. View at Publisher · View at Google Scholar · View at Scopus
  39. L. Gölz, S. Memmert, B. Rath-Deschner et al., “LPS from P. gingivalis and hypoxia increases oxidative stress in periodontal ligament fibroblasts and contributes to periodontitis,” Mediators of Inflammation, vol. 2014, Article ID 986264, 13 pages, 2014. View at Publisher · View at Google Scholar
  40. C. Jian, C. Li, Y. Ren et al., “Hypoxia augments lipopolysaccharide-induced cytokine expression in periodontal ligament cells,” Inflammation, vol. 37, no. 5, pp. 1413–1423, 2014. View at Publisher · View at Google Scholar · View at Scopus
  41. H. Motohira, J. Hayashi, J. Tatsumi, M. Tajima, H. Sakagami, and K. Shin, “Hypoxia and reoxygenation augment bone-resorbing factor production from human periodontal ligament cells,” Journal of Periodontology, vol. 78, no. 9, pp. 1803–1809, 2007. View at Publisher · View at Google Scholar · View at Scopus
  42. A. R. Terrizzi, J. Fernandez-Solari, C. M. Lee et al., “Alveolar bone loss associated to periodontal disease in lead intoxicated rats under environmental hypoxia,” Archives of Oral Biology, vol. 58, no. 10, pp. 1407–1414, 2013. View at Publisher · View at Google Scholar · View at Scopus
  43. A. Kumar, L. Rani, B. Dhole, and P. K. Chaturvedi, “Oxygen as a regulator of MA-10 cell functions: effect of cobalt chloride on vascular endothelial growth factor production,” Andrologia, vol. 44, no. 1, pp. 615–620, 2012. View at Publisher · View at Google Scholar · View at Scopus
  44. A. Kumar, L. Rani, and B. Dhole, “Role of oxygen in the regulation of Leydig tumor derived MA-10 cell steroid production: the effect of cobalt chloride,” Systems Biology in Reproductive Medicine, vol. 60, no. 2, pp. 112–118, 2014. View at Publisher · View at Google Scholar
  45. K. Lin, P. Ye, J. Liu, F. He, and W. Xu, “Endostar inhibits hypoxia-induced cell proliferation and migration via the hypoxia-inducible factor-1α/vascular endothelial growth factor pathway in vitro,” Molecular Medicine Reports, 2014. View at Publisher · View at Google Scholar
  46. S. Ambrosini, E. Sarchielli, P. Comeglio et al., “Fibroblast growth factor and endothelin-1 receptors mediate the response of human striatal precursor cells to hypoxia,” Neuroscience, vol. 289, pp. 123–133, 2015. View at Publisher · View at Google Scholar
  47. K. S. Kim, V. Rajagopal, C. Gonsalves, C. Johnson, and V. K. Kalra, “A novel role of hypoxia-inducible factor in cobalt chloride- and hypoxia-mediated expression of IL-8 chemokine in human endothelial cells,” Journal of Immunology, vol. 177, no. 10, pp. 7211–7224, 2006. View at Publisher · View at Google Scholar · View at Scopus
  48. S.-H. Hsu, C.-T. Chen, and Y.-H. Wei, “Inhibitory effects of hypoxia on metabolic switch and osteogenic differentiation of human mesenchymal stem cells,” Stem Cells, vol. 31, no. 12, pp. 2779–2788, 2013. View at Publisher · View at Google Scholar · View at Scopus
  49. Shweta, K. P. Mishra, S. Chanda, S. B. Singh, and L. Ganju, “A comparative immunological analysis of CoCl2 treated cells with in vitro hypoxic exposure,” Biometals, vol. 28, no. 1, pp. 175–185, 2015. View at Publisher · View at Google Scholar
  50. T. Osathanon, P. Vivatbutsiri, W. Sukarawan, W. Sriarj, P. Pavasant, and S. Sooampon, “Cobalt chloride supplementation induces stem-cell marker expression and inhibits osteoblastic differentiation in human periodontal ligament cells,” Archives of Oral Biology, vol. 60, no. 1, pp. 29–36, 2015. View at Publisher · View at Google Scholar
  51. H.-H. Kim, S. E. Lee, W. J. Chung et al., “Stabilization of hypoxia-inducible factor-1α is involved in the hypoxic stimuli-induced expression of vascular endothelial growth factor in osteoblastic cells,” Cytokine, vol. 17, no. 1, pp. 14–27, 2002. View at Publisher · View at Google Scholar · View at Scopus
  52. P. Gupta, S. Nath, R. Meena, and N. Kumar, “Comparative effects of hypoxia and hypoxia mimetic cobalt chloride on in vitro adhesion, biofilm formation and susceptibility to amphotericin B of Candida glabrata,” Journal de Mycologie Médicale, vol. 24, no. 4, pp. e169–e177, 2014. View at Publisher · View at Google Scholar
  53. T. L. McCarthy, Z. Yun, J. A. Madri, and M. Centrella, “Stratified control of IGF-I expression by hypoxia and stress hormones in osteoblasts,” Gene, vol. 539, no. 1, pp. 141–151, 2014. View at Publisher · View at Google Scholar · View at Scopus
  54. R. J. Custodio, V. I. do Carmo Custodio, C. A. Scrideli et al., “Impact of hypoxia on IGF-I, IGF-II, IGFBP-3, ALS and IGFBP-1 regulation and on IGF1R gene expression in children,” Growth Hormone and IGF Research, vol. 22, no. 5, pp. 186–191, 2012. View at Publisher · View at Google Scholar · View at Scopus
  55. D. Ekinci, S. B. Ceyhun, E. Aksakal, and O. Erdoǧan, “IGF and GH mRNA levels are suppressed upon exposure to micromolar concentrations of cobalt and zinc in rainbow trout white muscle,” Comparative Biochemistry and Physiology C Toxicology and Pharmacology, vol. 153, no. 3, pp. 336–341, 2011. View at Publisher · View at Google Scholar · View at Scopus
  56. Y.-H. Joung, M.-Y. Lee, E.-J. Lim et al., “Hypoxia activates the IGF-1 expression through STAT5b in human HepG2 cells,” Biochemical and Biophysical Research Communications, vol. 358, no. 3, pp. 733–738, 2007. View at Publisher · View at Google Scholar · View at Scopus
  57. D. Xing and J. A. Bonanno, “Hypoxia reduces TGFbeta1-induced corneal keratocyte myofibroblast transformation,” Molecular Vision, vol. 15, pp. 1827–1834, 2009. View at Google Scholar · View at Scopus