Epigenetic Contribution of High-Mobility Group A Proteins to Stem Cell Properties

Table 1

Wnt/β-catenin, miR-let-7, HMGA2, and EZH2 action in mesenchymal stem cells (MSCs) differentiation.

Differentiation lineage	Canonical Wnt	miR let-7	HMGA2	EZH2
Adipogenesis	−	−	+	+
Osteogenesis	+	+	−	−
Myogenesis
Early	+	+	−	−
Late	−
Cardiogenesis	−	+	−	−

(+): positive contribution; (−): negative contribution.