Exploring Seipin: From Biochemistry to Bioinformatics Predictions

Figure 9

Differently expressed genes during seipin loss-of-function. InteractVenn [43] allowed us to see four different clusters formed when seipin loses its function in different cell types. iRegulon [44] shows HNF4A, CEBPB, ZNF740, and RORC as important transcription factors that may interfere with the expression of the observed genes for each cluster. Among them, only CEBPB was studied in a loss of seipin function [45].