Asporin Reduces Adult Aortic Valve Interstitial Cell Mineralization Induced by Osteogenic Media and Wnt Signaling Manipulation <i>In Vitro</i>

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left"></td><td class="align_left"></td><td class="align_center">OS+rhAsp-conditioned AVICs</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Negative regulatory molecule of bone cell differentiation</td><td class="align_center"><i>Asporin</i></td><td class="align_center">Upregulated</td></tr><tr><td class="align_center" colspan="3"><hr/></td></tr><tr><td class="align_left">Osteogenic marker genes</td><td class="align_center"><i>Osteopontin</i>, <i>Runx2</i></td><td class="align_center">Downregulated</td></tr><tr><td class="align_center" colspan="3"><hr/></td></tr><tr><td class="align_left" rowspan="3">Wnt signaling-specific markers genes</td><td class="align_center"><i>β-Catenin</i></td><td class="align_center">Downregulated</td></tr><tr><td class="align_center"><i>Wnt3a</i></td><td class="align_center">Downregulated</td></tr><tr><td class="align_center"><i>Dkk1</i></td><td class="align_center">Upregulated</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>qRT-PCR results of comparison between OS-induced control and OS+rhAsp-treated AVICs.</div>

International Journal of Cell Biology

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Table 3: Asporin Reduces Adult Aortic Valve Interstitial Cell Mineralization Induced by Osteogenic Media and Wnt Signaling Manipulation <i>In Vitro</i> 

International Journal of Cell Biology

Asporin Reduces Adult Aortic Valve Interstitial Cell Mineralization Induced by Osteogenic Media and Wnt Signaling Manipulation In Vitro

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