Table 1: CHI-containing devices used for bone and nerve tissue regeneration in humans.

DeviceTissueTimeReference

CHI ascorbate gelperiodontium2 months[35]
Me-pyrrolidinone-CHI geltooth alveolar bone6 months[36]
DCMC-CaPa gel or solutionmandible bone15 days[41]
CHI conduits with PGAb filamentsright arm median nerve36 months[86]

aN,N-dicarboxymethyl CHI with calcium phosphate;
bpoly(glycolic acid).