Table of Contents
International Journal of Carbohydrate Chemistry
Volume 2013, Article ID 846565, 7 pages
http://dx.doi.org/10.1155/2013/846565
Research Article

Analgesic Activity of a Glucan Polysaccharide Isolated from Agaricus blazei Murill

1Department of Organic and Inorganic Chemistry, Federal University of Ceará, P.O. Box 12200, 60455-760 Fortaleza, CE, Brazil
2Department of Biochemistry and Molecular Biology, Federal University of Ceará, P.O. Box 12200, 60455-760 Fortaleza, CE, Brazil

Received 9 July 2013; Revised 30 July 2013; Accepted 31 July 2013

Academic Editor: R. J. Linhardt

Copyright © 2013 Maria Leônia C. Gonzaga et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. S. Yim, F. Y. Chye, S. M. Koo, P. Matanjun, S. E. How, and C. W. Ho, “Optimization of extraction time and temperature for antioxidant activity of edible wild mushroom, Pleurotus porrigens,” Food and Bioproducts Processing, vol. 90, no. 2, pp. 235–242, 2012. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Y. Lee, J. Y. Kim, Y. G. Lee, M. H. Rhee, E. K. Hong, and J. Y. Cho, “Molecular mechanism of macrophage activation by exopolysaccharides from liquid culture of Lentinus edodes,” Journal of Microbiology and Biotechnology, vol. 18, no. 2, pp. 355–364, 2008. View at Google Scholar · View at Scopus
  3. C. G. Son, J. W. Shin, J. H. Cho et al., “Macrophage activation and nitric oxide production by water soluble components of Hericium erinaceum,” International Immunopharmacology, vol. 6, no. 8, pp. 1363–1369, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. E. R. Carbonero, C. R. Andrea, C. S. Freitas et al., “Chemical and biological properties of a highly branched beta-glucan from edible mushroom Pleurotus sajor-caju,” Carbohydrate Polymers, vol. 90, pp. 814–819, 2012. View at Google Scholar
  5. S. R. Suseem, S. A. Mary, R. P. Neelakanda, and G. Marslin, “Evaluation of the analgesic activity of ethyl acetate, methanol and aqueous extracts of Pleurotus eous mushroom,” Asian Pacific Journal of Tropical Medicine, vol. 4, no. 2, pp. 117–120, 2011. View at Publisher · View at Google Scholar · View at Scopus
  6. P. Manzi, L. Gambelli, S. Marconi, V. Vivanti, and L. Pizzoferrato, “Nutrients in edible mushrooms: an inter-species comparative study,” Food Chemistry, vol. 65, no. 4, pp. 477–482, 1999. View at Publisher · View at Google Scholar · View at Scopus
  7. A. T. Southgate, K. Waldron, I. T. Johnson, and G. R. Fenwich, “Dietary fibre: chemical and biological aspects,” Special Publication 83, Royal Society of Chemistry, 1990. View at Google Scholar
  8. P. C. K. Cheung, “Plasma and hepatic cholesterol levels and fecal neutral sterol excretion are altered in hamsters fed straw mushroom diets,” Journal of Nutrition, vol. 128, no. 9, pp. 1512–1516, 1998. View at Google Scholar · View at Scopus
  9. H. Kawagishi, T. Kanao, R. Inagaki et al., “Formolysis of a potent antitumor (1 → 6)-β-d-glucan-protein complex from Agaricus blazei fruiting bodies and antitumor activity of the resulting products,” Carbohydrate Polymers, vol. 12, no. 4, pp. 393–403, 1990. View at Google Scholar · View at Scopus
  10. T. Mizuno, T. Hagiwara, T. Nakamura, H. Ito, K. Shimura, and T. Sumiya, “Antitumoraktivity and some properties of water-soluble polysaccharides from Himematsutake, the fruiting body of Agaricus blazei Murill,” Agricultural and Biological Chemistry, vol. 54, pp. 2889–2896, 1990. View at Google Scholar
  11. H.-L. Chang, G.-R. Chao, C.-C. Chen, and J.-L. Mau, “Non-volatile taste components of Agaricus blazei, Antrodia camphorata and Cordyceps militaris mycelia,” Food Chemistry, vol. 74, no. 2, pp. 203–207, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Nikkarinen and E. Mertanen, “Impact of geological origin on trace element composition of edible mushrooms,” Journal of Food Composition and Analysis, vol. 17, no. 3-4, pp. 301–310, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. L. Rácz, L. Papp, V. Oldal, and Z. Kovács, “Determination of essential and toxic metals in cultivated champignons by inductively coupled plasma atomic emission spectrometry,” Microchemical Journal, vol. 59, no. 2, pp. 181–186, 1998. View at Google Scholar · View at Scopus
  14. V. Mohaček-Grošev, R. Božac, and G. J. Puppels, “Vibrational spectroscopic characterization of wild growing mushrooms and toadstools,” Spectrochimica Acta A, vol. 57, no. 14, pp. 2815–2829, 2001. View at Publisher · View at Google Scholar · View at Scopus
  15. V. E. C. Ooi and F. Liu, “Immunomodulation and anti-cancer activity of polysaccharide-protein complexes,” Current Medicinal Chemistry, vol. 7, no. 7, pp. 715–729, 2000. View at Google Scholar · View at Scopus
  16. P. Manzi and L. Pizzoferrato, “Beta-glucans in edible mushrooms,” Food Chemistry, vol. 68, no. 3, pp. 315–318, 2000. View at Publisher · View at Google Scholar · View at Scopus
  17. P. Orlean, “Biogenesis of yeast cell wall and surface components,” in The Molecular and Cellular Biology of the Yeast Saccharomyces, J. R. Pringle, J. R. Broach, and E. W. Jones, Eds., vol. 3 of Cell Cycle and Cell Biology, pp. 229–362, Cold Spring Harbor Laboratory Press, New York, NY, USA, 1997. View at Google Scholar
  18. Y. Sun, J. Tang, X. Gu, and D. Li, “Water-soluble polysaccharides from Angelica sinensis (Oliv.) Diels: preparation, characterization and bioactivity,” International Journal of Biological Macromolecules, vol. 36, no. 5, pp. 283–289, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. T. B. Ng, “A review of research on the protein-bound polysaccharide (polysaccharopeptide, PSP) from the mushroom Coriolus versicolor (basidiomycetes: polyporaceae),” General Pharmacology, vol. 30, no. 1, pp. 1–4, 1998. View at Publisher · View at Google Scholar · View at Scopus
  20. D. Rout, S. Mondal, I. Chakraborty, and S. S. Islam, “The structure and conformation of a water-insoluble (1→3)-,(1→6)-β-d-glucan from the fruiting bodies of Pleurotus florida,” Carbohydrate Research, vol. 343, no. 5, pp. 982–987, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. M. S. Shiao, K. R. Lee, J. J. Lin, and C. T. Wang, Food Phytochemicals For Cancer Prevention II: Teas, Spices and Herbs, The American Chemical society, Washington, DC, USA, 1994.
  22. S. C. Jong and J. M. Birmingham, “Medicinal benefits of the mushroom Ganoderma,” Advances in Applied Microbiology, vol. 37, pp. 101–134, 1992. View at Google Scholar · View at Scopus
  23. C.-W. Lieu, S.-S. Lee, and S.-Y. Wang, “The effect of Ganoderma lucidum on induction of differentiation in leukemic U937 cells,” Anticancer Research, vol. 12, no. 4, pp. 1211–1215, 1992. View at Google Scholar · View at Scopus
  24. W. D. Jarvis, A. J. Turner, L. F. Povirk, R. S. Traylor, and S. Grant, “Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C,” Cancer Research, vol. 54, no. 7, pp. 1707–1714, 1994. View at Google Scholar · View at Scopus
  25. L. C. Faccin, F. Benati, V. P. Rincão et al., “Antiviral activity of aqueous and ethanol extracts and of an isolated polysaccharide from Agaricus brasiliensis against poliovirus type 1,” Letters in Applied Microbiology, vol. 45, no. 1, pp. 24–28, 2007. View at Publisher · View at Google Scholar · View at Scopus
  26. J. P. F. Angeli, L. R. Ribeiro, M. L. C. Gonzaga et al., “Protective effects of β-glucan extracted from Agaricus brasiliensis against chemically induced DNA damage in human lymphocytes,” Cell Biology and Toxicology, vol. 22, no. 4, pp. 285–291, 2006. View at Publisher · View at Google Scholar · View at Scopus
  27. M. L. C. Gonzaga, Agaricus Blazei Murill: Isolamento, Caracterização Estrutural e Atividades Biológicas dos Polissacarídeos e/ou Glicoconjugados Presentes [Ph.D. thesis], Federal University of Ceará, Ceará, Brazil, 2006.
  28. Y. Yoshioka, R. Tabeta, H. Saitó, N. Saitó, and F. Fukuoka, “Antitumor Polysaccharides From P. Ostreatus (Fr.) Quél.: Isolation and Structure of a beta-Glucan,” Carbohydrate Research, vol. 140, pp. 93–100, 1985. View at Google Scholar
  29. M. Dubois, K. A. Gilles, J. K. Hamilton, P. A. Rebers, and F. Smith, “Colorimetric method for determination of sugars and related substances,” Analytical Chemistry, vol. 28, no. 3, pp. 350–356, 1956. View at Google Scholar · View at Scopus
  30. M. Pramanik, S. Mondal, I. Chakraborty, D. Rout, and S. S. Islam, “Structural investigation of a polysaccharide (Fr. II) isolated from the aqueous extract of an edible mushroom, Pleurotus sajor-caju,” Carbohydrate Research, vol. 340, no. 4, pp. 629–636, 2005. View at Publisher · View at Google Scholar · View at Scopus
  31. E. F. Hartree, “Determination of protein: a modification of the lowry method that gives a linear photometric response,” Analytical Biochemistry, vol. 48, no. 2, pp. 422–427, 1972. View at Google Scholar · View at Scopus
  32. M. M. Bradford, “A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding,” Analytical Biochemistry, vol. 72, no. 1-2, pp. 248–254, 1976. View at Google Scholar · View at Scopus
  33. W. C. Vander and S. Margolin, “Analgesic tests based upon exerimentally induced acute abdominal pain in rats,” Federation Proceedings, vol. 15, article 494, 1956. View at Google Scholar
  34. R. Koster, M. Anderson, and J. Beer, “Acetic acid for analgesic screening,” Federation Proceedings, vol. 18, pp. 412–414, 1959. View at Google Scholar
  35. M. L. C. Gonzaga, N. M. P. S. Ricardo, F. Heatley, and S. D. A. Soares, “Isolation and characterization of polysaccharides from Agaricus blazei Murill,” Carbohydrate Polymers, vol. 60, no. 1, pp. 43–49, 2005. View at Publisher · View at Google Scholar · View at Scopus
  36. S. Saito, Y. Sasaki, T. Furumoto, S. Sumita, and T. Hinomoto, “Virtual 1H-1H spin-spin coupling in a linear five-spin system on the pyranose rings of some glucuronides,” Carbohydrate Research, vol. 258, pp. 59–75, 1994. View at Publisher · View at Google Scholar · View at Scopus
  37. R. M. Silvestein, G. C. Bassler, and T. C. Morrill, Identificação Espectrométrica de Compostos Orgânicos, Guanabara Koogan, 1994.
  38. I. Chakraborty, S. Mondal, M. Pramanik, D. Rout, and S. S. Islam, “Structural investigation of a water-soluble glucan from an edible mushroom, Astraeus hygrometricus,” Carbohydrate Research, vol. 339, no. 13, pp. 2249–2254, 2004. View at Publisher · View at Google Scholar · View at Scopus
  39. Y. Ukawa, H. Ito, and M. Hisamatsu, “Antitumor effects of (1→3)-β-D-glucan and (1→6)-β-D-glucan purified from newly cultivated mushroom, Hatakeshimeji (Lyophyllum decastes Sing.),” Journal of Bioscience and Bioengineering, vol. 90, no. 1, pp. 98–104, 2000. View at Publisher · View at Google Scholar · View at Scopus
  40. T. Longvah and Y. G. Deosthale, “Compositional and nutritional studies on edible wild mushroom from northeast India,” Food Chemistry, vol. 63, no. 3, pp. 331–334, 1998. View at Publisher · View at Google Scholar · View at Scopus
  41. A. Demirbaş, “Concentrations of 21 metals in 18 species of mushrooms growing in the East Black Sea region,” Food Chemistry, vol. 75, no. 4, pp. 453–457, 2001. View at Publisher · View at Google Scholar · View at Scopus
  42. L. C. Hendershot and J. Forsaith, “Antagonism of the frequency of phenylquinone-induced writhing in the mouse by weak analgesics and nonanalgesics,” Journal of Pharmacology and Experimental Therapeutics, vol. 125, pp. 237–240, 1959. View at Google Scholar
  43. B. J. Northover, “The permeability to plasma proteins of the peritoneal blood vessels of the mouse, and the effect of substances that alter permeability,” The Journal of pathology and bacteriology, vol. 85, pp. 361–370, 1963. View at Google Scholar · View at Scopus
  44. L. A. P. Vieira, Estudos Bioquímicos e Farmacológicos das Algas, Bryothamnion seaforthii, Bryothamnion triquetrum e Bottuocladia occidentalis [M.S. thesis], Federal University of Ceará, Ceará, Brazil,, 2002.
  45. L. Pires, P. A. J. Gorin, F. Reicher, and M.-R. Sierakowski, “An active heparinoid obtained by sulphation of a galactomannan extracted from the endosperm of Senna macranthera seeds,” Carbohydrate Polymers, vol. 46, no. 2, pp. 165–169, 2001. View at Publisher · View at Google Scholar · View at Scopus