Table of Contents
International Journal of Carbohydrate Chemistry
Volume 2015 (2015), Article ID 235763, 7 pages
http://dx.doi.org/10.1155/2015/235763
Research Article

A New Generation of Glycoconjugated Azo Dyes Based on Aminosugars

1Department of Pharmacy, University of Pisa, Via Bonanno 33, 56126 Pisa, Italy
2School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland

Received 7 May 2015; Revised 13 July 2015; Accepted 14 July 2015

Academic Editor: Vladimir Kren

Copyright © 2015 Lorenzo Guazzelli et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The third generation of glycoconjugated azo dyes (GADs) was prepared linking monoazo dyes to 6-amino-6-deoxy-d-galactose or 6′amino-6′-deoxylactose through mixed amido-ester connections. The complementary conjugation reactions were studied using the succinyl derivative of either the acetal protected aminosugar or the azo dye. Target “naturalized” GADs were obtained after acid hydrolysis of the acetal protecting groups present on the sugar moiety.