International Journal of Chronic Diseases / 2014 / Article / Tab 2

Clinical Study

Evaluation of Rhubarb Supplementation in Stages 3 and 4 of Chronic Kidney Disease: A Randomized Clinical Trial

Table 2

Haemogram and renal function tests in control and Rhubarb groups before and after 12 weeks of treatment.

Serial number ParameterGroup0 week
mean ± SD
12 weeks
mean ± SD
% change after 12 weeks95% confidence interval

1Hb%
(g/dL)
I7.91 ± 1.938.91 ± 1.48c(+) 12.64%(−) 1.24 to (−) 0.75
II7.87 ± 2.069.05 ± 1.58c1(+) 14.99%(−) 1.51 to (−) 0.85

2FBG
(mg/dL)
I130.05 ± 42.90113.78 ± 14.31c(−) 12.51%8.88 to 23.64
II132.60 ± 45.55107.20 ± 18.03c2(−) 19.15%14.97 to 35.82

3PPBG
(mg/dL)
I184.95 ± 61.17157.56 ± 23.20c(−) 14.80%17.38 to 37.40
II182.30 ± 62.05147.65 ± 15.46c2(−) 19.00%23.17 to 46.11

4B. Urea
(mg/dL)
I107.16 ± 35.8579.78 ± 24.79b(−) 25.55%21.83 to 32.92
II108.89 ± 42.6572.25 ± 20.89c1(−) 33.64%30.97 to 42.30

5S.Cr.
(mg/dL)
I4.44 ± 1.643.33 ± 1.37c(−) 25.00%0.86 to 1.37
II4.06 ± 2.082.82 ± 1.11 c1(−) 30.54%0.91 to 1.55

6K+
(mEq/L)
I4.87 ± 0.494.63 ± 0.41a(−) 4.92%0.27 to 0.41
II4.84 ± 0.444.42 ± 0.48b2(−) 8.67%0.26 to 0.57

7Ca2+
(mg/dL)
I8.65 ± 1.058.89 ± 1.00a(+) 2.77%) 0.53 to 0.07
II8.72 ± 1.019.38 ± 0.90b2(+) 7.56%(−) 0.93 to (−) 0.38

8TUP
(g/day)
I3.03 ± 1.292.43 ± 0.97b(−) 19.80%0.35 to 0.85
II3.18 ± 1.572.12 ± 0.65c1(−) 30.18%0.83 to 1.09

9TUV
(mL/day)
I1454.36 ± 221.531736.76 ± 176.04c(+) 19.41%(−) 333.40 to (−) 230.38
II1451.69 ± 303.741870.14 ± 258.78c3(+) 28.82%(−) 467.28 to (−) 369.61

10GFR
(mL/min)
I19.0 ± 1.1723.3 ± 1.63b(+) 22.6%5.28 to 9.73
II19.1 ± 2.3728.0 ± 3.51c3(+) 46.5%5.99 to 15.31

Values are mean ± SD; was considered significant; a, b, c compared to 0 week value of respective group; 1, 2, 3 compared to control group. I: control; II: Rhubarb; Hb%: haemoglobin percent; FBG: fasting blood glucose; PPBG: postprandial blood glucose; B. urea: blood urea; S.Cr.: serum creatinine; K+: serum potassium; Ca2+: serum calcium; TUP: 24 hour total urine protein; TUV: 24 hour total urine volume; GFR: glomerular filtration rate; (−) decrease; and (+) increase.

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