Hierarchical Modeling of Patient and Physician Determinants of Blood Pressure Outcomes in Hypertensive Patients with and without Diabetes: Pooled Analysis of Six Observational Valsartan Studies with 15,282 Evaluable Patients
Table 1
Studies included in pooled analysis.
PREVIEW
IMPROVE
INSIST
eNOVA
SCORE
EXCELLENT
Total
Study characteristics
Year initiated
2004
2004
2006
2006
2008
2008
Diabetic
627
781
225
253
815
957
3658
Nondiabetic
2424
2818
470
701
2622
2589
11624
Number of physicians
504
684
308
284
354
698
2832
PREVIEW
IMPROVE
INSIST
eNOVA
SCORE
EXCELLENT
Weighted average
Patient characteristics
Age, y, mean (±SD)
Male gender (%)
47.7
48.7
48.5
49.0
52.3
53.9
50.5
Valsartan formulation
80 mg
✓
✓
✓
✓
160 mg
✓
✓
✓
✓
80/12.5 mg HCTZ
✓
✓
✓
✓
160/12.5 mg HCTZ
✓
✓
✓
160/25 mg HCTZ
✓
✓
✓
80/5 mg amlodipine
✓
160/5 mg amlodipine
✓
160/10 mg amlodipine
✓
HCTZ: hydrochlorothiazide; SD: standard deviation.