Clinical Study

Reduction of Liver Span and Parameters of Inflammation in Nonalcoholic Fatty Liver Disease Patients Treated with Lycosome Formulation of Phosphatidylcholine: A Preliminary Report

Table 1

Baseline characteristics.

Baseline characteristics of the enrolled patients
 (mean ± SD) 
VariablePC-LycosomePC

Number of patients1415
Males89
Females66
Age49.1 ± 4.851.2 ± 5.7
Light/moderate smokers45
Body mass index29.5 ± 3.328.4 ± 3.8
AST in U/L39.14 ± 3.7738.71 ± 3.19
ALT in U/L60.50 ± 5.5460.78 ± 5.05
Fasting glucose in mmol/L5.5 ± 0.496.2 ± 0.61
Total cholesterol in mg/Dl272.0 ± 15.5262.3 ± 14.2
Triglycerides in mg/Dl128 ± 12.6129 ± 12.9
LDL in mg/Dl220 ± 19.2207 ± 17.2
HDL in mg/Dl43.3 ± 3.941.4 ± 3.3
Pulse rate per min71.8 ± 4.272.1 ± 5.3
Blood pressure in mm Hg
 Systolic121.5 ± 7.9120.8 ± 6.4
 Diastolic75.7 ± 5.275.1 ± 6.0
Liver size in cm
 Mid-clavicular line16.10 ± 0.5816.2 ± 0.60
 Mid-sternal line7.19 ± 0.437.12 ± 0.34

The patients were screened, enrolled, and randomized into two major groups for the study as described in Materials and Methods. Baseline characteristics from the time point “0” of the study were expressed as mean values with standard deviations and are shown above.