Association of CCL2, CCR5, ELMO1, and IL8 Polymorphism with Diabetic Nephropathy in Malaysian Type 2 Diabetic Patients

Table 9

The odd ratio of polymorphism in association with T2DM and nephropathy.

	Malay				Chinese				Indian
	Allele		Genotype		Allele		Genotype		Allele		Genotype
	Multiplicative Model; a vs. A	Additive Model; AA vs aa Aa vs aa	Dominant Model; AA; vs. Aa + aa	Recessive Model; AA + Aa; vs. aa	Multiplicative Model; a vs. A	Additive Model; AA vs aa; Aa vs aa	Dominant Model; AA; vs. Aa + aa	Recessive Model; AA + Aa; vs. aa	Multiplicative Model; a vs. A	Additive Model; AA vs aa Aa vs aa	Dominant Model; AA; vs. Aa + aa	Recessive Model; AA + Aa; vs. aa
CCR5					2.46	6.71	0.31	3.79	-	-	-	-
rs1799987	-	-	-	-	(1.62-3.71)	(2.55-17.68)	(0.12-0.56)	(1.56-9.22)
(G/A)						2.52
						(0.99-6.39)
IL8					-	-	-	-	1.42	1.57	0.46	0.94
rs4073	-	-	-	-					(0.96-2.10)	(0.66-3.71)	(0.26-0.83)	(0.43-2.04)
(T/A)										0.66
										(0.29-1.48)

ODD Ratio (OR), 95% CI. A: the major allele; a: the minor allele or increased risk.