Hybrid Anion Exchange Hollow Fiber Membrane for Delivery of Ionic Drugs

Table 3

Diffusion coefficients (𝐷/×10⁻⁶ cm²/s) of different drugs from BPPO-γ-MPS(+) hollow fiber membrane at 37°C under different outer phase conditions, calculated by the Higuchi equation (3).

Outer phase conditions	NaBS	NaSA	NaMAS	NaLS
Pure water	16.79	1.456	0.4714	35.44
PBS at pH 5.0	1483	218.8	100.8	1598
PBS at pH 7.4	1327	123.9	77.42	4531
PBS at pH 9.0	1429	39.36	345.0	3803
PBS with 100 mg/dL Glc and 70 mg/mL BSA, pH 7.4	161.7	132.1	72.61	353.6