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International Journal of Chemical Engineering
Volume 2016 (2016), Article ID 5217802, 9 pages
Research Article

Optimal Extraction of Gallic Acid from Suaeda glauca Bge. Leaves and Enhanced Efficiency by Ionic Liquids

Jiangsu Provincial Key Laboratory of Coastal Wetland Bioresources and Environmental Protection, School of Chemistry and Chemical Engineering, Yancheng Teachers University, Xiwang Road, Yancheng, Jiangsu 224051, China

Received 23 November 2015; Revised 4 January 2016; Accepted 11 January 2016

Academic Editor: Alírio Rodrigues

Copyright © 2016 Xin-Hong Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The ultrasound-assisted extraction (UAE) was initially applied to extract gallic acid from Suaeda glauca Bge. using 70% ethanol as extraction solvent. Temperature, liquid-solid ratio, and extraction time were optimized by response surface methodology (RSM), obtaining maximum levels of gallic acid (6.30 mg·g−1) at 51°C, 19.52 mL·g−1, and 42.68 min, respectively. The obtained model was statistically significant (). The verification experiments at the optimum conditions yielded gallic acid for 6.21 mg·g−1. Subsequently, under optimal conditions, four ionic liquids were used to extract gallic acid from Suaeda glauca Bge. The results indicated that the presence of 1-hexyl-3-methylimidazolium chloride allowed increasing the EE of gallic acid up to 8.90 mg·g−1. This might be interpreted in terms of the molecular interaction between ionic liquid and gallic acid. The use of ionic liquids involves a stronger gallic acid extraction capacity than conventional organic volatile solvents. A promising alternative process is proposed for the extraction of gallic acid of Suaeda glauca Bge.