Determination of Cortisol and Dehydroepiandrosterone Levels in Saliva for Screening of Periodontitis in Older Japanese Adults

Table 3

Median values for salivary cortisol and dehydroepiandrosterone in presence or absence of extensive periodontitis in subjects who never smoked, divided by PD and CAL.

	Categories divided by PD*
	None	Low	High	𝑃 value^†
Number	59	41	13
Cortisol (ng/mL)
Median	1.68	2.32	3.10	.002
(25th, 75th percentile)	(1.29, 2.40)	(1.58, 3.31)	(2.08, 3.62)
DHEA (pg/mL)
Median	47.22	68.99	119.01	<.001
(25th, 75th percentile)	(28.50, 70.29)	(37.49, 97.93)	(79.67, 137.93)
Salivary flow rate (mL/min)
Median	0.90	0.97	0.90	.578
(25th, 75th percentile)	(0.67, 1.13)	(0.67, 1.33)	(0.60, 1.52)
	Categories divided by CAL*
	None	Low	High	𝑃 value^†
Number	67	32	14
Cortisol (ng/mL)
Median	1.64	2.49	2.98	<.001
(25th, 75th percentile)	(1.29, 2.39)	(1.75, 3.10)	(1.84, 3.67)
DHEA (pg/mL)
Median	54.28	66.60	104.44	.003
(25th, 75th percentile)	(28.50, 76.69)	(41.57, 111.30)	(68.62, 122.41)
Salivary flow rate (mL/min)
Median	0.93	1.08	0.75	.092
(25th, 75th percentile)	(0.67, 1.17)	(0.73, 1.38)	(0.31, 1.06)

*Defined by the number of teeth (no teeth, less than 3 teeth, 3 or more teeth) with PD  ≥5 mm or CAL  ≥6 mm. DHEA: dehydroepiandrosterone. PD: probing depth (mm). CAL: clinical attachment loss (mm). ^†Kruskal-Wallis test.