Determination of Cortisol and Dehydroepiandrosterone Levels in Saliva for Screening of Periodontitis in Older Japanese Adults

Table 4

Median values for salivary cortisol and dehydroepiandrosterone in presence or absence of extensive periodontitis in subjects who smoked, divided by PD and CAL.

	Categories divided by PD*
	None	Low	High	𝑃 value^†
Number	28	22	8
Cortisol (ng/mL)
Median	2.01	2.13	2.44	.573
(25th, 75th percentile)	(1.41, 3.13)	(1.36, 2.73)	(1.98, 3.13)
DHEA (pg/mL)
Median	36.72	48.70	94.75	.173
(25th, 75th percentile)	(28.44, 82.12)	(30.07, 89.77)	(46.67, 121.26)
Salivary flow rate (mL/min)
Median	0.87	0.80	0.92	.494
(25th, 75th percentile)	(0.51, 1.26)	(0.29, 1.19)	(0.69, 1.25)
	Categories divided by CAL*
	None	Low	High	𝑃 value^†
Number	26	18	14
Cortisol (ng/mL)
Median	2.01	2.09	2.59	.243
(25th, 75th percentile)	(1.29, 2.58)	(1.42, 3.09)	(1.68, 3.43)
DHEA (pg/mL)
Median	45.12	44.30	55.98	.633
(25th, 75th percentile)	(32.99, 85.14)	(19.49, 95.35)	(30.54, 114.47)
Salivary flow rate (mL/min)
Median	0.90	0.88	0.59	.079
(25th, 75th percentile)	(0.66, 1.21)	(0.57, 1.56)	(0.29, 1.05)

*Defined by the number of teeth (no teeth, less than 3 teeth, 3 or more teeth) with PD  ≥5 mm or CAL  ≥6 mm. DHEA: dehydroepiandrosterone. PD: probing depth (mm). CAL: clinical attachment loss (mm). ^†Kruskal-Wallis test.