International Journal of Dentistry / 2010 / Article / Tab 9

Review Article

Gene Polymorphisms in Chronic Periodontitis

Table 9

FcγRIIa, FcγRIIIa, and FcγRIIIb gene polymorphisms and carriage rate of the Rare (R)-allele in case-control studies and association with susceptibility to chronic periodontitis.

PatientsControls
geneEthnicitynR-alleleNR-alleleAssociatedReference
polymorphismof subjectscarriagecarriagewith periodontitis

IIa 131 H>RCaucasian 5476%2471% Colombo et al. 1998 [70]
Caucasian5670%6175% Loos et al. 2003 [71]
Caucasian21363%20975% ( )Yamamoto et al. 2004 [72]
Caucasian13272%7274% Wolf et al. 2006 [73]
Japanese 10044%10540% Kobayashi et al. 1997 [74]
Japanese 8346%10439% Kobayashi et al. 2000 [75]
Japanese8942%6442% Kobayashi et al. 2001 [76]
Taiwanese5050%7462% Chung et al. 2003 [77]
Japanese58 48%4436% Kobayashi et al. 2007 [19]
Japanese100 44%10039% Kobayashi et al. 2007 [20]

IIIa 158 F>VCaucasian5673%6159% Loos et al. 2003 [71]
Japanese 10042%10446% Sugita et al. 1999 [78]
Japanese 8343%10446% Kobayashi et al. 2000 [75]
Japanese8949%6439% Kobayashi et al. 2001 [76]
Japanese58 40%4445% Kobayashi et al. 2007 [19]
Japanese100 45%10045% Kobayashi et al. 2007 [20]

IIIb NA1> NA2Caucasian 5489%2475% Colombo et al. 1998 [70]
Caucasian5688%6192% Loos et al. 2003 [71]
Caucasian13284%7289% Wolf et al. 2006 [73]
Japanese 10063%10564% Kobayashi et al. 1997 [74]
Japanese 8364%10464% Kobayashi et al. 2000 [75]
Japanese8962%6456% Kobayashi et al. 2001 [76]
Japanese 7374%4656% Sugita et al. 2001 [79]
Japanese 5258%5557% Yoshihara et al. 2001 [80]
Taiwanese5062%7455% Chung et al. 2003 [77]
Japanese58 66%4455% Kobayashi et al. 2007 [19]
Japanese100 66%10064% Kobayashi et al. 2007 [20]

nr = not reported. = association not found. = association found.
Mainly Caucasian, actual % of subjects of non-Caucasian heritage is not provided.
Cases diagnosed as adult periodontitis.
Cases diagnosed as mixed periodontitis status
N-allele is associated with periodontitis in smokers.