International Journal of Dentistry / 2011 / Article / Tab 1

Research Article

Evaluation by an Aeronautic Dentist on the Adverse Effects of a Six-Week Period of Microgravity on the Oral Cavity

Table 1

The median (range) unstimulated salivary whole flow rate, compositions, biomarkers (sodium, potassium, calcium, phosphate, protein, lactate dehygrogenase, MIP 1 alpha, malonaldehyde, 8-hydroxydeoxyguanosine, thiocyanate, amylase activity, vitamins E, C), and mouth opening before and during last day of HDT in 10 healthy persons.

ParametersBefore HDTLast day of HDT 𝑃 value

Flow rate (mL/min)0.026 (0.01–0.03)0.009 (0.008–0.02)<0.01
Na (mM)13 (8.0–15.0)12 (9.0–18.2)<0.01
K (mM)23.6 (6.7–34.8)22.2 (7.3–36.9)<0.05
Total calcium (mM)3.4 (1.4–4.6)3.9 (2.4–4.8)<0.01
Total phosphate (mM)7.4 (1.3–11.3)7.8 (2.1–12.1)<0.01
Total protein (mg/mL)4.4 (1.6–13.6)4.5 (1.7–14.2)<0.05
Cl (Mm)22.3 (14.9–42.1)22.0 (14.7–43.2)<0.05
Total protein output (mg/min)0.44 (0.23–0.96)0.42 (0.26–0.85)<0.001
Amylase activity (micro kat/L)324 (145–567)262 (112–345)<0.001
Vitamins E (mg/mL)0.56 (0.32–0.76)0.51 (0.31–0.73)<0.005
Vitamins C (mg/mL)0.35 (0.12–54)0.32 (0.09–0.52)<0.05
Lactate dehygrogenase (IU/L)2.4 (1.2–3.4)2.3 (1.6–3.7)<0.05
MIP 1 alpha (pg/mL)17.6 (12.6–21.5)18.1 (13.2–22.4)<0.01
Malonaldehyde (ng/mL)2.46 (1.45–4.34)2.65 (1.67–4.89)<0.05
8-hydroxydeoxyguanosine (ng/mL)0.66 (0.45–1.34)0.78 (0.51–1.43)<0.001
Thiocyanate (U/L)34.3 (21.7–56.9)39.8 (22.7–57)<0.001
Mouth opening (In cm)45.4 (34.6–53.2)42.3 (31.5–49.6)<0.005

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