International Journal of Dentistry / 2012 / Article / Fig 4

Review Article

The Current and Future Therapies of Bone Regeneration to Repair Bone Defects

Figure 4

BMP2-induced ectopic bone formation in vivo is enhanced in the presence of a selective inhibitor of NF-κB, BAY11-7082. Two micrograms of BMP2 was implanted subcutaneously to induce ectopic bone formation in the presence or absence of BAY11-7082 in mice ( ). (a) μCT reconstruction images of ectopic bone in the presence or absence of BAY11-7082 in mice. Bar: 1 mm. (b) Bone mineral density (BMD) of the ectopic bone in the presence or absence of BAY11-7082 was measured by dual-energy X-ray absorptiometry (DXA). * .
148261.fig.004a
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148261.fig.004b
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