Local Regeneration of Dentin-Pulp Complex Using Controlled Release of FGF-2 and Naturally Derived Sponge-Like Scaffolds
Figure 2
Controlled release of FGF-2. Gelatin hydrogels has an ability to incorporate growth factors such as FGF-2. After implantation of gelatin hydrogels incorporating FGF-2 with scaffolds, such as collagen sponge, FGF-2 is gradually released from gelatin hydrogels biodegraded by proteinase at tissue defect area. The controlled released FGF-2 can induce tissue regeneration.