Review Article

Local Regeneration of Dentin-Pulp Complex Using Controlled Release of FGF-2 and Naturally Derived Sponge-Like Scaffolds

Figure 2

Controlled release of FGF-2. Gelatin hydrogels has an ability to incorporate growth factors such as FGF-2. After implantation of gelatin hydrogels incorporating FGF-2 with scaffolds, such as collagen sponge, FGF-2 is gradually released from gelatin hydrogels biodegraded by proteinase at tissue defect area. The controlled released FGF-2 can induce tissue regeneration.
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