Bone Regeneration in Artificial Jaw Cleft by Use of Carbonated Hydroxyapatite Particles and Mesenchymal Stem Cells Derived from Iliac Bone
Figure 3
Radiographic findings before and after the transplantation of MSCs to artificial jaw cleft. Standardized occlusal X-ray images (a) after preparation of bilateral artificial jaw cleft in maxilla, (b) before and (c) after transplantation of MSCs with CAP particles to the jaw cleft (3 months after the preparation of artificial jaw cleft; arrowhead, jaw cleft). The cleft on the right side (control side) was filled with CAP particles alone, whereas the cleft on the left side (experimental side) was filled with MSCs and CAP particles, (d) 3 months and (e) 6 months after the transplantation (arrowhead, transplanted area). (f) The radio-opacity of the artificial jaw cleft area was measured on the standardized occlusal X-ray images after the transplantation to the artificial jaw cleft. The signals of regenerated bone and CAP particles were evaluated by radio-opacity of the jaw cleft area. , *, **.
